Ring Finger Protein 216 (RNF216) (N-Term) Peptide
RNF216
Reactivité: Humain, Souris
Hôte: Synthetic
BP, WB
N° du produit ABIN2185638
Aperçu rapide pour Ring Finger Protein 216 (RNF216) (N-Term) Peptide (ABIN2185638)
Antigène
RNF216
(Ring Finger Protein 216 (RNF216))
Origine
Humain, Souris
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Rnf216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNF216 (Ring Finger Protein 216 (RNF216))
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Sujet
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Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.
Protein Size: 853 -
Poids moléculaire
- 93 kDa
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ID gène
- 108086
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UniProt
- P58283
Antigène
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